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Local LLMs that run on AMD Ryzen AI Max+ 395 (128 GB)

By this directory's rule of thumb, 42 of 63 open-weight models fit in the 128 GB of unified memory on the Ryzen AI Max+ 395. The largest by total parameters is Mistral Medium 3.5 128B (127.7B), whose smallest non-MLX download is 74.9 GB, the Q4_K_M GGUF build from unsloth/Mistral-Medium-3.5-128B-GGUF.

Models that fit
42 of 63
Memory
128 GB
Memory type
LPDDR5x unified (256-bit)
Bandwidth
Not stated

Spec sheet

Memory
128 GB
Memory type
LPDDR5x unified (256-bit)
Unified memory
Yes, shared by CPU and GPU
Bandwidth
Not stated

AMD lists Max. Memory 128 GB of 256-bit LPDDR5x up to LPDDR5x-8000 shared between CPU and Radeon 8060S Graphics; the spec page states no bandwidth figure or launch date.

Source: AMD spec page (amd.com)

42 models that fit in 128 GB

Total params, largest first
42 open-weight models that fit in the 128 GB Ryzen AI Max+ 395, by total parameters, largest first
ModelTotal paramsSmallest downloadQuantCommercial
Mistral Medium 3.5 128BMistral AI127.7B74.9 GBQ4_K_MGGUFCommercial use: Conditions
Devstral 2 123B Instruct 2512Mistral AI125B74.9 GBQ4_K_MGGUFCommercial use: Conditions
NVIDIA Nemotron 3.5 Super VL 120B-A12BNVIDIA124.5B12B active71.8 GBQ4_0GGUFCommercial use: Yes
Mistral Small 4 119B (2603)Mistral AI119.4B6.5B active73.8 GBUD-Q4_K_MGGUFCommercial use: Yes
gpt-oss-120bOpenAI116.8B5.1B active62.8 GBQ4_K_MGGUFCommercial use: Yes
Cohere Command A (03-2025)Cohere111.1B67.1 GBQ4_K_MGGUFCommercial use: No
GLM-4.5-AirZ.ai110.5B12B active73.0 GBQ4_K_MGGUFCommercial use: Yes
Llama 4 Scout 17B-16E InstructMeta108.6B17B active65.4 GBQ4_K_MGGUFCommercial use: Conditions
GLM-4.6VZ.ai107.7B70.6 GBQ4_K_MGGUFCommercial use: Yes
Qwen3-Coder-NextAlibaba Cloud (Qwen)79.7B3B active48.4 GBQ4_K_MGGUFCommercial use: Yes
NVIDIA Nemotron 3.5 Bolt 74B-A9BNVIDIA74.9B9B active22.0 GB24GB (native 2-bit)GGUFCommercial use: Yes
AI21 Jamba2 MiniAI21 Labs51.6B12B active31.2 GBQ4_K_MGGUFCommercial use: Yes
Qwen3.6-35B-A3BAlibaba Cloud (Qwen)36B3B active22.1 GBUD-Q4_K_MGGUFCommercial use: Yes
Cohere Aya Expanse 32BCohere32.3B19.8 GBQ4_K_MGGUFCommercial use: No
Ai2 Olmo 3.1 32B ThinkAi232.2B19.5 GBQ4_K_MGGUFCommercial use: Yes
NVIDIA Nemotron 3.5 Lightning 30B-A3BNVIDIA31.6B3B active18.9 GBQ4_0GGUFCommercial use: Yes
Gemma 4 31BGoogle31.3B17.7 GBQ4_0 (QAT)GGUFCommercial use: Yes
IBM Granite 4.2 30BIBM29.3B17.7 GBQ4_K_MGGUFCommercial use: Yes
Qwen3.8-27BAlibaba Cloud (Qwen)27.8B16.5 GBUD-Q4_K_MGGUFCommercial use: Yes
Gemma 4 26B A4BGoogle25.8B3.8B active14.4 GBQ4_0 (QAT)GGUFCommercial use: Yes
Devstral Small 2 24B Instruct 2512Mistral AI24B14.3 GBQ4_K_MGGUFCommercial use: Yes
Liquid AI LFM2.5-24B-A2BLiquid AI24B2.5B active14.5 GBQ4_K_MGGUFCommercial use: Conditions
gpt-oss-20bOpenAI20.9B3.6B active11.6 GBQ4_K_MGGUFCommercial use: Yes
Phi-4-reasoning-vision-15BMicrosoft15.1B30.2 GBBF16Official weightsCommercial use: Yes
Phi-4Microsoft14.7B9.1 GBQ4_KGGUFCommercial use: Yes
Phi-4-reasoning-plusMicrosoft14.7B9.1 GBQ4_K_MGGUFCommercial use: Yes
Ministral 3 14B Instruct 2512Mistral AI13.9B8.2 GBQ4_K_MGGUFCommercial use: Yes
Gemma 4 12BGoogle12B7.0 GBQ4_0 (QAT)GGUFCommercial use: Yes
Qwen3.5-9BAlibaba Cloud (Qwen)9.7B5.7 GBQ4_K_MGGUFCommercial use: Yes
Ministral 3 8B Instruct 2512Mistral AI8.9B5.2 GBQ4_K_MGGUFCommercial use: Yes
IBM Granite 4.2 8BIBM8.8B5.3 GBQ4_K_MGGUFCommercial use: Yes
Cohere Command R7B (12-2024)Cohere8B5.1 GBQ4_K_MGGUFCommercial use: No
Gemma 4 E4BGoogle8B5.0 GBQ4_K_MGGUFCommercial use: Yes
Ai2 Olmo Hybrid Instruct DPO 7BAi27.4B14.9 GBBF16Official weightsCommercial use: Yes
Gemma 4 E2BGoogle5.1B3.1 GBQ4_K_MGGUFCommercial use: Yes
Qwen3.5-4BAlibaba Cloud (Qwen)4.7B2.7 GBQ4_K_MGGUFCommercial use: Yes
Ministral 3 3B Instruct 2512Mistral AI3.8B2.1 GBQ4_K_MGGUFCommercial use: Yes
Phi-4-mini-instructMicrosoft3.8B2.5 GBQ4_K_MGGUFCommercial use: Yes
Phi-4-mini-reasoningMicrosoft3.8B2.5 GBQ4_K_MGGUFCommercial use: Yes
Liquid AI LFM2.5-2.6BLiquid AI2.7B1.7 GBQ4_K_MGGUFCommercial use: Conditions
Qwen3.5-2BAlibaba Cloud (Qwen)2.3B1.3 GBQ4_K_MGGUFCommercial use: Yes
Qwen3.5-0.8BAlibaba Cloud (Qwen)0.9B0.5 GBQ4_K_MGGUFCommercial use: Yes

The rest of the 63 need more than 128 GB. Browse every local model.

Same memory size. Each shows how many models fit under its own rule (Macs also count MLX builds), and the memory type and bandwidth differ.

Compare all 33 GPUs and Macs by memory, bandwidth and how many models fit.

FAQ

How many local LLMs can the Ryzen AI Max+ 395 run?

42 of the 63 open-weight models in this directory fit, with 128 GB of unified memory, by this site's rule of thumb that the smallest non-MLX download is at most 85% of the memory. MLX builds do not count here: they run on Apple silicon only.

Can the Ryzen AI Max+ 395 run Mistral Medium 3.5 128B?

Yes, by this directory's rule of thumb: its smallest non-MLX download, 74.9 GB, is at most 85% of 128 GB (108.8 GB), the Q4_K_M GGUF build from unsloth/Mistral-Medium-3.5-128B-GGUF. That leaves room for the context and the operating system. It is a memory check, not a speed estimate.

Can the Ryzen AI Max+ 395 run NVIDIA Nemotron 3.5 Super VL 120B-A12B?

Yes, by this directory's rule of thumb: its smallest non-MLX download, 71.8 GB, is at most 85% of 128 GB (108.8 GB), the Q4_0 GGUF build from ggml-org/NVIDIA-Nemotron-3.5-Super-VL-120B-A12B-GGUF. That leaves room for the context and the operating system. It is a memory check, not a speed estimate.

Can the Ryzen AI Max+ 395 run Step 3.7 Flash?

Not by this directory's rule of thumb: its smallest non-MLX download, 111.5 GB, is more than 85% of 128 GB (108.8 GB). It needs the 256 GB tier or more: https://www.developersdigest.tech/local-models/fits/256.

Is the Ryzen AI Max+ 395's memory shared with the operating system?

Yes. AMD lists LPDDR5x unified (256-bit) memory shared by the CPU and GPU, so the operating system and your apps use the same pool as the model. The 15% headroom in this directory's rule is there for that and for the context.

What memory bandwidth does the Ryzen AI Max+ 395 have?

AMD's spec page does not state a bandwidth figure, so this page shows Not stated. The memory is LPDDR5x unified (256-bit).

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