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NVIDIA - workstation GPU - verified

Local LLMs that run on NVIDIA RTX PRO 5000 Blackwell (up to 72 GB)

By this directory's rule of thumb, 33 of 63 open-weight models fit in the 72 GB of VRAM on the RTX PRO 5000 Blackwell in its largest configuration. The largest by total parameters is Qwen3-Coder-Next (79.7B), whose smallest non-MLX download is 48.4 GB, the Q4_K_M GGUF build from Qwen/Qwen3-Coder-Next-GGUF.

Models that fit
33 of 63
Memory
Up to 72 GB
Memory type
GDDR7 ECC
Bandwidth
1,344 GB/s

Spec sheet

Memory
Up to 72 GB
Configurations
48 or 72 GB
Memory type
GDDR7 with ECC
Unified memory
No
Bandwidth
1,344 GB/s

Offered in 48 GB and 72 GB GDDR7 with ECC configurations, with 1,344 GB/sec memory bandwidth listed on the spec page.

Source: NVIDIA spec page (nvidia.com)

33 models that fit in 72 GB

Total params, largest first
33 open-weight models that fit in the 72 GB RTX PRO 5000 Blackwell, by total parameters, largest first
ModelTotal paramsSmallest downloadQuantCommercial
Qwen3-Coder-NextAlibaba Cloud (Qwen)79.7B3B active48.4 GBQ4_K_MGGUFCommercial use: Yes
NVIDIA Nemotron 3.5 Bolt 74B-A9BNVIDIA74.9B9B active22.0 GB24GB (native 2-bit)GGUFCommercial use: Yes
AI21 Jamba2 MiniAI21 Labs51.6B12B active31.2 GBQ4_K_MGGUFCommercial use: Yes
Qwen3.6-35B-A3BAlibaba Cloud (Qwen)36B3B active22.1 GBUD-Q4_K_MGGUFCommercial use: Yes
Cohere Aya Expanse 32BCohere32.3B19.8 GBQ4_K_MGGUFCommercial use: No
Ai2 Olmo 3.1 32B ThinkAi232.2B19.5 GBQ4_K_MGGUFCommercial use: Yes
NVIDIA Nemotron 3.5 Lightning 30B-A3BNVIDIA31.6B3B active18.9 GBQ4_0GGUFCommercial use: Yes
Gemma 4 31BGoogle31.3B17.7 GBQ4_0 (QAT)GGUFCommercial use: Yes
IBM Granite 4.2 30BIBM29.3B17.7 GBQ4_K_MGGUFCommercial use: Yes
Qwen3.8-27BAlibaba Cloud (Qwen)27.8B16.5 GBUD-Q4_K_MGGUFCommercial use: Yes
Gemma 4 26B A4BGoogle25.8B3.8B active14.4 GBQ4_0 (QAT)GGUFCommercial use: Yes
Devstral Small 2 24B Instruct 2512Mistral AI24B14.3 GBQ4_K_MGGUFCommercial use: Yes
Liquid AI LFM2.5-24B-A2BLiquid AI24B2.5B active14.5 GBQ4_K_MGGUFCommercial use: Conditions
gpt-oss-20bOpenAI20.9B3.6B active11.6 GBQ4_K_MGGUFCommercial use: Yes
Phi-4-reasoning-vision-15BMicrosoft15.1B30.2 GBBF16Official weightsCommercial use: Yes
Phi-4Microsoft14.7B9.1 GBQ4_KGGUFCommercial use: Yes
Phi-4-reasoning-plusMicrosoft14.7B9.1 GBQ4_K_MGGUFCommercial use: Yes
Ministral 3 14B Instruct 2512Mistral AI13.9B8.2 GBQ4_K_MGGUFCommercial use: Yes
Gemma 4 12BGoogle12B7.0 GBQ4_0 (QAT)GGUFCommercial use: Yes
Qwen3.5-9BAlibaba Cloud (Qwen)9.7B5.7 GBQ4_K_MGGUFCommercial use: Yes
Ministral 3 8B Instruct 2512Mistral AI8.9B5.2 GBQ4_K_MGGUFCommercial use: Yes
IBM Granite 4.2 8BIBM8.8B5.3 GBQ4_K_MGGUFCommercial use: Yes
Cohere Command R7B (12-2024)Cohere8B5.1 GBQ4_K_MGGUFCommercial use: No
Gemma 4 E4BGoogle8B5.0 GBQ4_K_MGGUFCommercial use: Yes
Ai2 Olmo Hybrid Instruct DPO 7BAi27.4B14.9 GBBF16Official weightsCommercial use: Yes
Gemma 4 E2BGoogle5.1B3.1 GBQ4_K_MGGUFCommercial use: Yes
Qwen3.5-4BAlibaba Cloud (Qwen)4.7B2.7 GBQ4_K_MGGUFCommercial use: Yes
Ministral 3 3B Instruct 2512Mistral AI3.8B2.1 GBQ4_K_MGGUFCommercial use: Yes
Phi-4-mini-instructMicrosoft3.8B2.5 GBQ4_K_MGGUFCommercial use: Yes
Phi-4-mini-reasoningMicrosoft3.8B2.5 GBQ4_K_MGGUFCommercial use: Yes
Liquid AI LFM2.5-2.6BLiquid AI2.7B1.7 GBQ4_K_MGGUFCommercial use: Conditions
Qwen3.5-2BAlibaba Cloud (Qwen)2.3B1.3 GBQ4_K_MGGUFCommercial use: Yes
Qwen3.5-0.8BAlibaba Cloud (Qwen)0.9B0.5 GBQ4_K_MGGUFCommercial use: Yes

2 more models fit in 72 GB only as an MLX build, which runs on Apple silicon only: GLM-4.5-Air and Llama 4 Scout 17B-16E Instruct.

The rest of the 63 need more than 72 GB. Browse every local model.

By memory configuration

NVIDIA sells the RTX PRO 5000 Blackwell with 48 or 72 GB. The same rule applied to each configuration, and the models each step up adds.

NVIDIA RTX PRO 5000 Blackwell: models that fit in each memory configuration
ConfigurationModels that fitLargest that fitsNew at this size
48 GB32 / 63NVIDIA Nemotron 3.5 Bolt 74B-A9BBase configuration: 32 models
72 GB33 / 63Qwen3-Coder-NextQwen3-Coder-Next

Compare all 33 GPUs and Macs by memory, bandwidth and how many models fit.

FAQ

How many local LLMs can the RTX PRO 5000 Blackwell run?

33 of the 63 open-weight models in this directory fit in its largest configuration, 72 GB, by this site's rule of thumb that the smallest non-MLX download is at most 85% of the memory. By configuration: 32 at 48 GB and 33 at 72 GB. MLX builds do not count here: they run on Apple silicon only.

Can the RTX PRO 5000 Blackwell run Qwen3-Coder-Next?

Yes, by this directory's rule of thumb: its smallest non-MLX download, 48.4 GB, is at most 85% of 72 GB (61.2 GB), the Q4_K_M GGUF build from Qwen/Qwen3-Coder-Next-GGUF. That leaves room for the context. It is a memory check, not a speed estimate.

Can the RTX PRO 5000 Blackwell run NVIDIA Nemotron 3.5 Bolt 74B-A9B?

Yes, by this directory's rule of thumb: its smallest non-MLX download, 22.0 GB, is at most 85% of 72 GB (61.2 GB), the 24GB (native 2-bit) GGUF build from nvidia/NVIDIA-Nemotron-3.5-Bolt-74B-A9B-24GB-GGUF. That leaves room for the context. It is a memory check, not a speed estimate.

Can the RTX PRO 5000 Blackwell run gpt-oss-120b?

Not by this directory's rule of thumb: its smallest non-MLX download, 62.8 GB, is more than 85% of 72 GB (61.2 GB). It needs the 128 GB tier or more: https://www.developersdigest.tech/local-models/fits/128.

Can the RTX PRO 5000 Blackwell use system RAM for bigger models?

This page only counts models that fit entirely in the 72 GB of VRAM. Runtimes can offload layers to system RAM, but this directory does not list or measure that.

What memory bandwidth does the RTX PRO 5000 Blackwell have?

NVIDIA states 1,344 GB/s of memory bandwidth (GDDR7 with ECC). From the spec notes: Offered in 48 GB and 72 GB GDDR7 with ECC configurations, with 1,344 GB/sec memory bandwidth listed on the spec page. This page does not turn bandwidth into a speed estimate.

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